Resveratrol & IVF: Does It Hurt Implantation? New Research Explained with Dr. Mark Ratner 

Lorne Brown 

Out there, people are concerned about taking resveratrol because they’ve been told it could impact implantation. So don’t take it if you’re after ovulation, don’t take it around your transfer. But people are really happy based on the research to take it leading up to ovulation or leading up to an egg retrieval because it’s shown to help with egg quality. Can you talk on both the egg quality and the uterine side of it?

Mark Ratner 

The key here though is that, look, the retrospective studies showed a 43% reduction in pregnancy rates, which is, it sounds like a pretty dramatic number, but the trend in three of these four studies was towards improved pregnancy rates that just didn’t reach statistical significance. Yeah.

Lorne Brown 

By listening to the Coherence Code podcast, you agree to not use this podcast as medical advice to treat any medical condition either in yourself or others. Consult your own physician or healthcare provider for any medical issues that you may be having. This entire disclaimer also applies to any guests or contributors to the podcast. Welcome to the Coherence Code Podcast where we explore how the mind and body work together so you can move from stress and inner conflict to clarity, calm, and alignment. My name is Lorne Brown. I’m a doctor of traditional Chinese medicine and a clinical hypnotherapist. And through my work I’ve seen that healing happens when we remove what gets in the way and allow the body and the nervous system to do what they’re designed to do to heal. Welcome to the Coherence Code podcast.

Welcome back. We have Dr. Mark Ratner with us again, and this is a follow-up, Dr. Mark Ratner, we’ll discuss a little bit about his background, but this episode is because we did an episode on NAD support and he works over at theralogix. He’s their chief science officer and they have many supplements with respect to reproductive health. And one of the ones we were talking about is just NAD support, the different forms of the precursors and then other ingredients you can add. And in that discussion we were talking about resveratrol because they have a resveratrol like supplement inside their NAD support product. And we were having this discussion in real time. If you guys listen to the old episode where I’m on the internet digging, like I’ve heard really good things for resveratrol for egg quality, but I’ve heard not so good for transfer, it can affect uterine receptivity implantation.

And then Mark said, well, I have a study that says differently that it can help with implantation. Here is why. And so we said after the episode, let’s come back and discuss this because Mark says, I’m going to look into this. So this is us coming back. So the episode was just released before this, so go check all the wonderful things about NAD support and all the things marketing versus science that are out on the internet and on podcasts so you can learn about that and how you can support the cell and mitochondria health and NAD support. So that is there. Now we’re going to do a deep dive into resveratrol. So Mark, I would love for you to talk about being out there, people are concerned about taking resveratrol because they’ve been told it could impact implantation. So don’t take it if you’re after ovulation, don’t take it around your transfer. But people are really happy based on the research to take it leading up to ovulation or leading up to an egg retrieval because it’s shown to help with egg quality. Can you talk on both the egg quality and the uterine side of it? I would think because of time, I’d love to dive into the uterine side of it right away because that’s where there seems to be debate and you seem to have the most up-to-date information to share today.

Mark Ratner 

Yep. Well thanks Lorne for bringing us back together and letting us kind of do a deep dive into this interesting, really interesting subject. So the question that came up related to a study that was published back in 2019, it was a Japanese study and a retrospective study that looked at about 3000 women that they looked at and they identified about a hundred of those women. All these women were going through IVF. They identified about a hundred of those women who had taken resveratrol 200 milligrams per day leading up to their embryo transfer. And what they found was that there was about a 45% reduction in pregnancy rates in those women that the a hundred or so women that had taken resveratrol compared to the 2,900 women who had not had resveratrol. Actually, can I share my screen and I’ll show you a few of the actual data and we can talk through it as well.

Lorne Brown

So let’s share your screen there. And for our listeners, we have our YouTube channel where you can do this, you can watch it. And for those that are listening to audio only Mark has agreed to do a really good description of what we have on the screen.

Mark Ratner 

Absolutely. We’ll talk our way through this real quickly. So why is resveratrol of interest to begin with? Well, it’s because we know that resveratrol contains something called sirtuins. Okay. There are seven different sirtuins. These are enzymes that really function as the master regulators of cellular metabolism. So the seven different ones, they’re called cert one, cert two, cert three, cert four up to seven. And the first one, cert one. Those are really important for female reproductive health. And we know that with diminished ovarian reserve, either women who are in their late thirties, early forties, or it could even be in women with pathologic diminished ovarian reserve, younger women who have premature loss of ovarian reserve in those women cert one levels are reduced. And there’s been studies that show that if we can improve ovarian cert one levels, we will slow the loss of ovarian reserve and improve and quality

Lorne Brown 

And we can improve that. What you’re going to talk about with the red wine, the resveratrol, but also I think in fasting also, right? That also has been shown. Absolutely.

Mark Ratner 

Yep. Yep. Because one of the things that we understand is that sirtuins do the same thing that fasting does in that they activate something called mTOR or actually they suppress mTOR in doing that. They sort of really help with cellular longevity and health span. The other thing that we know about this sirtuin number one, what we call cert one, is that it is really important for endometrial development and what we call residualization. That means where the lining of the uterus essentially develops into a state that is receptive to the embryo. And so we need adequate levels in the uterine wall for embryo implantation. And there’s a study that was published that showed that in women with recurrent implantation failure where they’re going through IDF, good embryos, good quality embryos are being transferred, but they fail to implant. So we call that recurrent implantation failure. And those women, Sirtuin one levels are about 40% lower than normal.

Lorne Brown 

It’s interesting you say that. Can you go back to that slide? I’m just going to highlight a few things for the listeners that you shared. So you’re showing that sir one the sirtuins when they are reduced in women with administrative ovarian reserve, we’re seeing them redo. So we want to see a higher level of this. So increasing the cert one slows the loss of ovarian reserve and it facilitates uterine receptivity. And that’s important because for so many people it was like it’s all about the egg, all about the ovaries and that the uterus was just a container. And we now know that the uterus is also important, not just the egg blood flow, the immune system, all that’s important. So what’s happening with certain chemicals, enzymes, immune markers and inflammatory markers will impact, as you said, recurrent implantation failure. You’ve got chromosomally, normal looking embryos and yet they’re not implanting.

Mark Ratner 

Exactly. 

Lorne Brown 

This is about, hey, why are my embryos not sticking? And this is what you’re talking about here with respect to this.

Mark Ratner

Right, exactly. Alright, so how can we improve, Sirtuin one levels? Well, there’s a class of compounds that are called pterostilbene. They are plant derived and they have been shown to increase the activity of these cert or sirtuin enzymes. Resveratrol is actually the best known still beam. It’s probably the first one that was ever really scientifically explored. And resveratrol has been shown to increase sirtuin one levels. The problem is that as a supplement, resveratrol has some issues. The first issue is that it has poor absorption from the GI tract. There are other ways that people try to package it. They can put it in a liposomal type of formulation to improve absorption. But even if you get the absorption to improve a little bit, resveratrol still undergoes what’s called the first pass effect. And that means when it gets absorbed from the intestine in the lining of the intestine and in the liver, the resveratrol gets broken down into other metabolites and it’s actually 99% of the resveratrol that you absorb ends up getting broken down and only 1% of it ends up in the bloodstream as actual resveratrol. But it turns out that those other metabolites also have biological activity. Alright, so this was the study. The next slide here shows the study that we talked about last time.

Lorne Brown 

I want to highlight this because in prepping for our discussion today, that was one of the things that was highlighted, actually two things that I wanted to talk about. So I’m going to say it so you can bring it up. One is you just mentioned resveratrol, well-known, poorly absorbed. So it’s not what you take, it’s what you absorb. That counts. So although people are taking resveratrol, they may not be getting the benefit because it’s poorly absorbed. And this is why you’re going to talk about the pterostilbene idea that has been shown to be highly absorbed. The other thing, when you talk about the egg quality in mice, they do so well, we treat mice and we get such great results, but we don’t always translate into the human trials. So when you’re talking, can you share between mouse studies and human trials? I think we still don’t have the abundance of human trials, but I may find out different from talking to you

Mark Ratner 

Two. No, that’s exactly right. But there are some analogies between mice and men, female mice and women, and I’ll show you those in a sec. Okay. So this study that we talked about at the end of the last podcast was this Japanese study, 3000 women, a hundred of them roughly took 200 milligrams of resveratrol a day and a 43% lower pregnancy rate. Those women that took the resveratrol and the miscarriage rate increased by two and a half times. But if you go and you dive into this study, what you find out is that the women that took resveratrol had at baseline a significantly higher age when they came into this study. So the average resveratrol person was 39 and a half, the average control person was 37. And you might say, well that’s only two years. But those are crucial in terms of egg quality.

A two year difference between say 37 and 39 or 40, that’s a 25% increase in aneuploidy. In other words, the risk of an abnormal embryo chromosomally abnormal goes up by 25 to 30%. During those two years, the subjects that got resveratrol that took resveratrol, their AMH level was significantly lower. Their FSH level was significantly higher. They had almost double the use of ICSI compared to the resveratrol group compared to the non resveratrol Bruin and the resveratrol group had a lower average number of embryos transferred. So the point here is that there were a huge number of differences. This is the trouble with retrospective studies. The challenge is that when you’re not randomizing people prospectively, you’re not enrolling them in the study and flipping a coin to see which group they’re going to be in. When you look back retrospectively, it’s very hard to control for all of these other confounding variables. Okay,

Lorne Brown 

I have a question for you on that. Sure. So one is let’s just for reference purposes those listening. So the study is called the influence of resveratrol supplementation on IVF embryo transfer cycle outcomes.

Mark Ratner 

Correct.

Lorne Brown 

Repro biomed online 2019. So that’s that aspect. I just want to reference that. The other part is what you’re saying is that because it was retrospective study, meaning that the demographics weren’t the same, the people that were taking the was resveratrol who self-selected that were the tougher group, they already had factors that would show poorer outcomes in an IVF cycle.

Mark Ratner 

Exactly. They had a higher likelihood of poor quality embryos, poor quality eggs, and therefore poor quality embryos.

Lorne Brown 

You weren’t comparing apples to apples as they say.

Mark Ratner 

Exactly. And the authors though chose to sort of say that this was primarily an implantation issue where maybe it wasn’t. And again, and you look at the full paper, they don’t disclose what the form of resveratrol dosing was or how long these patients took it for. And they didn’t disclose the supplementation rationale. In other words, these women who decided on their own that they wanted to take resveratrol or were treating their healthcare provider say, I want you to take resveratrol for some reason, that basically they had higher risk of perhaps poor egg quality.

Lorne Brown 

So is this the 2019 study and is this the study that kind of switched people to put in the doubt that it may not be safe to take it during implantation? This is the study.

Mark Ratner 

Yeah, this was the first study that was published.

So if we go subsequently to this 2019 study, there have now actually been four more studies published which have been randomized prospective studies. In other words, where they enroll subjects women who are through IVF and half of them are controlled or placebo and the other half get resveratrol. And by doing that in a random way, you control for those other variables. And so the first study on the slide here was just a few months after that Japanese study. This was published in the Journal of Assisted Reproduction in Genetics. They had 61 women who were going through IVF because they had PCOS. This was a triple blinded randomized trial that women either were randomized to 800 milligrams of resveratrol or placebo. What did they find? They found that the resveratrol group had an increased number of high quality eggs and embryos, but they found no reduction in pregnancy rates in the resveratrol group. I want to repeat

Lorne Brown 

This because this got to land for people. So in that study, the second study in 2019 with resveratrol, those that were taking it, they had PCOS. You’re comparing apples to apples. Now the way it was, it was a retrospective study, correct? Am I understanding that correctly?

Mark Ratner

No, it was prospective. This was prospective. Oh, this one?

Lorne Brown 

Yeah, I meant to say. So it’s prospective, which is why they’re able to control the randomization apples to apples. And the group that did resveratrol had, can you share that again? Increased number of high quality eggs and embryos. So they saw better eggs and they saw better embryos and there was no change in pregnancy rates. So two things I want to ask or one thing is, the other study showed that there was a reduction and that’s where you were saying, I don’t think that’s a good study. The first one, this one saying it did not impact pregnancy rates. I have just one question. Did it not improve pregnancy rates then? I’m just curious about that.

Mark Ratner 

So if you look at the data when studies like this are published, they’re going to say, was it statistically significant or not? And in order to find statistical significance in certain endpoints like live birth rate or clinical pregnancy rate, you need really, really large studies. And so in this particular, I think in three of these four studies, there was a trend towards improved pregnancy rates, but it didn’t reach statistical significance because these were not huge studies. This was 61 patients when they did, just as an example, when they did the big study in PCOS patients that compared Clomid with Letrozole and was published in the New England Journal, this was NIH funded this study, they had 800 couples that they enrolled because that’s how big a study you need to show a statistically significant difference in an endpoint like pregnancy. So the key here though is that look, the retrospective study showed a 43% reduction in pregnancy rates, which sounds like a pretty dramatic number, but the trend in three of these four studies was towards improved pregnancy rates that just didn’t reach statistical significance.

Lorne Brown 

Yeah, I want to put my lens on it or repeat what you just said. There is a fear, a concern that resveratrol could impact implantation. So people stop taking it. And what you’re sharing here is first of all, we’re seeing, and you’re going to talk about other studies like that ICI study you sent me. There’s increase in egg quality, increase in embryo quality, increase in blasis rates, increase in all these things that you want to see, but statistically not an increase in pregnancy rates, but like you said, trending. So the point I want to make is trending to higher pregnancy rates not reducing. So the idea here is to do no harm. You’re saying by the most current research that may be a myth, and I tie this into that menopause study, the 2001 women’s health study where the women for 20 years didn’t suffer because there was a fear about HRT and now they’re saying, well those women, I’m just going to tangent.

The women in the study were all over 60. That’s not usually when you start HRT for women in menopause. Menopause, they use a synthetic progesterone. They think it was actually the progesterone, not the estrogen that caused the issue. Now they’re doing bioidentical, the dosage is different and they have a different delivery. So they show how flawed that study was and they even said it increased breast cancer. But then when they looked at the absolute, it was overstated and it was just a poorly presented study that changed how women were treated in perimenopause menopause for 25 years.

Mark Ratner 

Needlessly. Yeah, needlessly.

Lorne Brown

So I want to bring this up. There was one study that came out, it went viral and people stopped  resveratrol. No different than people having McDonald’s french fries to improve their transfer day. It’s great for intention, but just because somebody had french fries, if they had three IVF cycles that didn’t work. And then on one IVF cycle, they had french fries and that cycle worked and they told people, now everybody uses french fries on transfer day. That’s not science, but great intention, but it can stop. In this case what we’re talking about was resveratrol. My interpretation from our emails and our phone calls is that that 2019 study may be misleading and giving people the wrong information where they could still be benefiting. And the studies that you are showing now with the first one was that better egg, better embryo and trending in pregnancy rates not a decline. So let’s continue on because you’ve got more.

Mark Ratner 

Okay, so I’ll go through these other three studies really relatively quickly. In the 2021 Italian study, another double-blinded randomized trial, 101 women undergoing IVF. These were not PCOS women. They were treated either with a prenatal vitamin that included 150 milligrams of resveratrol or plain folic acid for 90 days prior to their egg retrieval. The resveratrol group had an increased number of eggs and better quality eggs and better fertilization rates. But again, no change reduction in pregnancy rates. The third study

Lorne Brown 

I’m going to highlight something, 90 days everybody, there’s that preconception. We always say a hundred days because of that whole follicular genesis. But remember it wasn’t just a week before their IVF, it was 90 days. So when you’re doing acupuncture, laser diet, all the supplements, everything you’re doing, you do want to give yourself some time. We always call it the hundred day preconception window here. The study was for 90 days, a good point. But again, improved higher quality of eggs, better fertilization rates, and there was not a decrease in pregnancy rates. So again, showing no harm.

Mark Ratner 

The third study, 2024, a journal of ovarian research, another double-blinded randomized trial, a placebo control, 56 women, 800 milligrams of resveratrol versus placebo for 60 days prior to IVF. Again, no reduction in pregnancy rates. And finally a fourth study published Italian study published in 2024, A journal of ovarian research. Again, this was a single blind and randomized trial with 70 women undergoing IVF, the same product, a prenatal vitamin with 150 milligrams of grace resveratrol versus placebo for 90 days. There were a bunch of positive findings, but including a reduced need for gonadotropins. In other words, their STEM cycle took less gonadotropins but no change, no reduction in pregnancy rates. So the take home here is that the four prospective trials that have been published in the last five years have not shown any reduction in pregnancy rates from use of resveratrol. Okay, so real quick, let’s just talk about terra still beam because it’s another still beam in the same family as resveratrol. So we consider it sort of an analog, meaning it’s chemically similar to resveratrol but it has better absorption and it really doesn’t undergo much of a first pass effect. So it doesn’t get broken down the same way that resveratrol does get broken down in the liver. Pterostilbene is naturally found in blueberries and peanuts and grapes and it very potently increases sirtuin one activity.

Lorne Brown 

Remind us sirtuin one. We like the sirtuin one being higher activity because absolutely better uterine receptivity and egg quality too, right?

Mark Ratner

And egg quality as well. So the point is that by decreasing the first pass effect, you don’t get those metabolites and so you reduce the risk of having what we call off target effects. You’re going to get primarily focused on sirtuin one activity here. Very safe Pterostilbenes used in doses up to 250 milligrams a day in randomized trials, but no really serious adverse offense or side effects. Okay,

Lorne Brown 

In your NAD support product, your pterostilbene, you said up to 250 safe, yours has a hundred milligrams. 

Mark Ratner 

A hundred milligrams, exactly. Yeah. So this is a study, it was published six months ago and incredibly, this is the same group from Japan that published the 2019 retrospective study. It’s the same OBGYN department, I’m sorry, in Japan. And they looked at Pterostilbene in aging mice. Okay. And so what was an aging mouse was I think it was either a 47 or 40 week old female mouse. So you might say what’s the equivalency? This is getting to the question that you posed a few minutes ago. Reproductively speaking, a 47 week old mouse is roughly equivalent to a woman who’s in the 40 to 45-year-old range in terms of reproductive function at 47 weeks. Female mice still cycle, but it’s often irregular. They have markedly reduced ovulation rates, lower egg quality, higher risk of aneuploidy, meaning the abnormal chromosome content in the egg that they produce with mitochondrial dysfunction and they have a reduction in litter size and implantation success.

So this was a really clever study. What they did was they took mice and they supplemented them with Pterostilbene for either one week, six weeks or 22 weeks. And when did they start these mice? They started them either one week before 47 weeks, six weeks before 47 weeks, meaning starting at 41 weeks of life or 22 weeks. So that was the long term. These were mice that started when they were 21 weeks old, or I’m sorry, 25 weeks old. And they took 22 weeks of terrace still beam. And then they looked at all of these outcomes when all of these mice were 47 weeks old. So here’s what it showed. And this is really a clever study, which is exciting. Okay, this graph right here, the gray bar, these are the young control mice. These are mice that are like eight, 10 weeks old.

Mice become fertile at like six weeks. So these are the number of eggs that get ovulated by young mice. Okay? The very dark bar here, these are 47 week old mice that had gotten no pterostilbene. And then the three bars next to it, this one week of pterostilbene. The next bar is six weeks of terrace still beam. And then the final bar is 22 weeks of pterostilbene. And so what you can see is that the longer these mice were given Pterostilbene, the better their number of ovulated eggs became at 47 weeks. The next outcome was implantation rate. Okay? Once again, the gray bar all the way to the left, these are young control mice. They have excellent implantation compared to the next bar, the black bar here, which is 47 week old mice. And you can see that at 47 weeks the implantation rate is down to 25% compared to over 80% in the young mice. But then when you start giving them, Tara, still being either for one week, six weeks or 22 weeks, you significantly improve implantation rate in these days.

Lorne Brown 

On the visual here, the 22 weeks are equivalent to the young control group.

Mark Ratner 

Oh yeah, it is, absolutely. It basically restored implantation to the same level as the young control group. This is the miscarriage rate. And young controls have about a 50% miscarriage rate. The 47 week old mice that got no Pterostilbene, it was over 80%. And then one week, six weeks or 22 weeks of Pterostilbene. You see a gradual reduction to the point where at 22 weeks your miscarriage rate is at or below what it is for young controls. And finally,

Lorne Brown 

Of course, so I just want to go back to the miscarriage rate when he said 22 weeks, that was 22 weeks of taking the Pterostilbene

Mark Ratner 

Being correct. That would be sort of like a woman starting to take Pterostilbene at the age of like 25 and continuing it till she was like 40. Okay, that’s a long period of exposure. Mice only lived for two years and typically by 18 months, mice have stopped ovulating completely. The last graph on the right here, which is arguably the most important one, is the live offspring rate. Okay? You look at the first bar gray controls compared to the second bar, which is the 47 week old mice without any Pterostilbene, a significant drop off in terms of the live offspring rate. But then with one week, six weeks or 22 weeks of terror still beam, you basically see at six weeks of terror still beam, you are essentially restoring the live birth rate to that of a young mouse. This is pretty exciting and compelling data. The same group in Japan is in the middle of a study. I think they’ve more or less tried to not, they obviously can’t do a 22 week study with women, but they’re doing a human study with terror still being alone in women undergoing IVF. And hopefully we will see the results of that sometime in the next year or so. So that’s what I want you to share.

Lorne Brown 

Yeah, I appreciate the deep dive. And again, I want to remind the listeners that there’s another episode with Dr. Mark Ratner where we’re talking about egg quality and NAD support. And he talks about Theralogix and what they’re using, they call it ova NAD plus and they have NR in it and Pterostilbene in it. And that’s how the discussion happened about resveratrol because it’s related to resveratrol. And we had this discussion about implantation and in live we were searching, as you heard me say at the beginning and after he said, I’m going to do a deep dive. And then we had some correspondence and he said, you know what, that was 2019, that was paper. That’s probably not a great paper. It was just what was out there, understandably, why people would react that way. But he goes, but we have new research.

And the one he just talked about was 2025. So he goes, we’ve got a lot more newer research, so let’s look at the current research. He sent it to me and I said, well, let’s get on and talk about it. So here we’re talking. So kind of takeaways in this idea, resveratrol, it’s shown so much benefit for a quality and a trending in pregnancy rates and it’s not even the best absorbed Pterostilbene. Is there a lot of, besides the one you showed in 2025, do we have many mice or human trials on that one yet on that form?

Mark Ratner 

So Pterostilbene has been studied not in reproductive health but in the health span type of blood pressure, peripheral vascular, peripheral circulation type of studies in combination with nicotinamide. Yeah, but there are no others, I’m trying to remember if there’s any other mouse studies with Pterostilbene

Lorne Brown 

But it has been studied, but not so much maybe in the form of reproductive health, but on a cellular level, which is what we’re always looking at. Exactly. And then if I could summarize what you said, and please correct, but the studies that you’ve shared so far that I got a chance to review, we’re seeing improvements in egg quality, improvements in embryo quality and also trending in increase in implantation. And then some of the studies you showed in the mice live birth rate. Absolutely. And so at this stage, you’re not seeing an issue with resveratrol or terra still being around implantation because a lot of people will stop it, but you’re not seeing that as legitimate at this point in time based on the research you’re looking at.

Mark Ratner 

I would say that’s an accurate summary. Exactly.

Lorne Brown 

And always talk to your healthcare provider. Remember this is educational, Dr. Mark is a doctor, he’s just not your doctor.

Mark Ratner 

Well put, very well put. So what I was going to say also is that in a lot of fertility practices these days, many practices had moved to a freeze ’em all approach, meaning they’re going to do your egg retrieval, they’re going to icsi the eggs, they’re going to basically then let the embryos go out to blast. They may do PGD if there’s any concern about the genetic quality of the embryos, and then they’ll freeze those embryos and that’s what they say, freeze ’em all. Okay. They freeze ’em all and then they let the woman recover from the whole STEM cycle and then a few weeks down the road they will go ahead and do the embryo transfer. And so in those instances, if there’s any doubt or concern, you would potentially stop the, because at that point your eggs have been retreated, your embryos have grown, and so there’s really no benefit in continuing something like ova NAD. The bottom line is if there’s still any concern on any listener’s part and there’s going to be a delay between the egg retrieval and icsi and then the embryo transfer, you simply just stop with NAD.

Lorne Brown 

The thing I’m thinking about is you talked about implantation failure and cert one, right? And so I’m just thinking though those that have implantation, those were like, what else maybe?

Mark Ratner 

Absolutely. If you’ve had recurrent implantation failure, this is something that you definitely want to be focused on. There’s no question about it. The other question that’s unanswered that we really don’t unfortunately have studies that are comprehensive enough to answer this question is how long if you stay on something like ola NAD for 90 days, 120 days, and then you stop it, how long does the benefit in terms of cert one levels in the endometrium, how long does that persist? Does it go away two days after you stop the supplement or does it persist for two weeks or two months? We just don’t know the answer to that question.

Lorne Brown 

And so in the episode before on NAD support, we talk about other ways to raise or one, so that’s in there in passing, when I was doing prep for our call, like n-acetyl-l-cysteine, one of my favorite supplements, it’s been shown to help with sirtuin one, and we’ve seen that in other studies with miscarriage and IVF diet, lifestyle, acupuncture, low level laser therapy, lots of ways to support that egg quality and uterine receptivity. 

Mark Ratner 

I think berberine will.

Lorne Brown 

Berberine, yeah. Yeah, there’s lots, again, it’s not like it’s the mechanism. What is it trying to do? And again, if you can get rid of the noise, so inflammation, oxidative stress, increased blood flow, the cells begin to thrive and you see all these other markers rise that you want to see in a healthy cell, including an egg cell or a uterine cell. So if you’re looking for more information, you can contact us at Acubalance. By the way, I set up discovery calls twice a week. They kind of put in my schedule where I can talk to people. So if you have questions, let us know. Theralogix is company that we’re talking with here today, Dr. Mark Ratner, and they have several fertility supplements for men and women, and one of them being for NAD support where they have pterostilbene in their product. So check them out as well. Dr. Mark, I enjoyed our conversation today. Thank you very much for sending all that research over. I appreciate it. 
Mark Ratner

My pleasure.

Lorne Brown

Always looking to learn. There’s always something to learn, right?

Mark Ratner

Thank you for having me.

Lorne Brown

All right, take good care.

Thank you for spending this with us on the Coherence Code podcast. I’m Dr. Lorne Brown, and I will see you next week for another conversation on coherence and healing. If this conversation resonated with you, please like, subscribe or follow the show and also share it with someone who might benefit from it as well. Remember to take a moment to breathe, reflect and stay connected.